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Tag Archives: obesity

How a protein works with gut bacteria to prevent obesity

Obesity is linked to higher levels of inflammation in the body, but the underlying mechanisms have remained unclear. Recently, however, a team of researchers has learned how one anti-inflammatory protein influences weight gain. There is a complex relationship between inflammation, gut bacteria, and obesity. A study paper recently published in the journal Cell Host & Microbe says that NLRP12, an ... Read More »

Obesity alters airway muscle function, increases asthma risk

New research suggests that obesity changes how airway muscles function, increasing the risk of developing asthma. The study is published ahead of print in the American Journal of Physiology — Lung Cellular and Molecular Physiology. The prevalence of asthma and obesity — as both separate and coexisting conditions — has grown considerably in the U.S. in recent years. Obesity is ... Read More »

Blocking this protein may keep obesity, diabetes at bay

Blocking a protein in the liver can prevent obesity and its related diseases — such as type 2 diabetes and fatty liver — in mice, according to new research. Have researchers found a new way to prevent obesity and its associated conditions? A study by Cincinnati Children’s Hospital Medical Center in Ohio reveals that a protein called Argonaute 2 (AGO2) ... Read More »

Scientists block RNA silencing protein in liver to prevent obesity and diabetes in mice

Obesity and its related ailments like type 2 diabetes and fatty liver disease pose a major global health burden, but researchers report in Nature Communications that blocking an RNA-silencing protein in the livers of mice keeps the animals from getting fat and diabetic conditions. Takahisa Nakamura, PhD, and colleagues at Cincinnati Children’s Hospital Medical Center genetically deleted a protein called ... Read More »

Obesity: We inherit the dangerous fat from Dad — and the good fat from Mom

A team of researchers, led by Professor Jan-Wilhelm Kornfeld from the Department of Biochemistry and Molecular Biology, University of Southern Denmark, Elena Schmidt from the Max Planck Institute for Metabolism Research, Cologne, Germany and Martin Bilban from the Medial University, Vienna, Austria, have made a groundbreaking discovery in obesity research. The team has discovered a new function of the gene ... Read More »

Exotic fruit may help fight obesity

An unusual fruit, native to the Amazon, may be useful in the fight against obesity and metabolic disorders by positively influencing gut bacteria. The camu camu packs a nutritional punch. Obesity increases the risk of metabolic diseases such as diabetes. By 2030, it is estimated that more than 1 billion people on earth will be overweight. So, understanding the mechanisms ... Read More »

Amazonian fruit prevents obesity in overfed mice

An extract of camu camu — a fruit native to the Amazon — prevents obesity in mice fed a diet rich in sugar and fat, say researchers at Université Laval and the Quebec Heart and Lung Institute Research Centre. The discovery, which was recently published in the scientific journal Gut, suggests that camu camu phytochemicals could play a leading role ... Read More »

The link between obesity, the brain, and genetics

Clinicians should consider how the way we think can make us vulnerable to obesity, and how obesity is genetically intertwined with brain structure and mental performance, according to new research. The study, led by researchers at the Montreal Neurological Institute and Hospital (The Neuro) and published in the Proceedings of the National Academy of Sciences on Aug. 28, 2018, was ... Read More »

Obesity, infertility and oxidative stress in mouse egg cells

Excessive body fat is associated with negative effects on female fertility and pregnancy. In mice, maternal obesity impairs proper development of egg precursor cells called oocytes. In a recent paper published in Molecular & Cellular Proteomics, Qiang Wang and colleagues at the State Key Laboratory of Reproductive Medicine in China describe the link between poor oocyte development and oxidative stress ... Read More »

Healthy fat cells uncouple obesity from diabetes

About 422 million people around the world, including more than 30 million Americans, have diabetes. Approximately ninety percent of them have type 2 diabetes. People with this condition cannot effectively use insulin, a hormone made by the pancreas that helps the body turn blood sugar (glucose) into energy. The inability to use insulin, called insulin resistance, results in increasing levels ... Read More »

‘Removing shoes outside house can help prevent obesity’

Obesity increasingly affects millions of people worldwide, with cases rising sharply in young children and babies – a trend which is not explained by evolving diets and lifestyles alone. Chemicals that interfere with how our bodies store and process fat are referred to as ‘obesogens’, and have been suggested as a possible contributor to the increasing number of obesity cases. ... Read More »

Drinking coffee during pregnancy ups obesity risk in kids: study

While the study published in the BMJ Open journal does not clearly show if caffeine is the direct cause of the excess weight, but the relationship, alone, has caused researchers to encourage increased caution. “There may be good cause to increase the restriction of the recommended maximum of three cups of coffee per day. Caffeine is not a medicine that ... Read More »